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The World Statistics Pocketbook, 2022 edition is the forty-sixth in a series of annual compilations of key statistical indicators prepared by the United Nations Statistics Division of the Department of Economic and Social Affairs. Over 50 indicators have been collected from more than 20 international statistical sources and are presented in one-page profiles for 30 world geographical regions and 232 countries or areas. The Pocketbook is organized into 5 sections; general information, economic indicators, major trading partners, social indicators, and environmental and infrastructure indicators. This issue presents data for the economic, social, environmental and infrastructure sections for three reference years - 2010, 2015 and 2022 - when available or the most recent data previous to these years, back to 2005, when it is not. For the general information and major trading partners sections the reference year is 2022 and 2021 respectively, unless otherwise footnoted. The indicators in the profiles cover the following topics: communication, crime, development assistance, education, energy, environment, finance, gender, health, international tourism, international trade, labor market, national accounts, population and migration, price and production indices and science and technology.